'Short sleep, shift work may raise risk of high BP'

SYDNEY: Short sleep lengths, daytime napping, shift work and even long sleep lengths have been linked to an increased risk of elevated blood pressure and cardiovascular disease, according to a new study.

The study, published in Nature Communications, is the first study to demonstrate that independent of other factors including age, sex and Body Mass Index (BMI), circadian rhythm-disrupting behaviours, including shift work, have an adverse effect on blood pressure regulation.

"We found that compromised sleep health or night shift work are associated with elevated blood pressure in both males and females and across all age groups," said lead author Morag Young, Associate Professor from the Baker Heart and Diabetes Institute in Melbourne.

"What we've found is that having circadian rhythms out of sync even slightly has an adverse impact on blood pressure," Young added.

The study found that permanent night shift workers who slept less than five or six hours were most at risk, but those working mixed shifts also showed elevated blood pressure. Interestingly, sleeping for too long a period also had a disruptive effect on circadian rhythms, Young said.

"Seven hours of sleep was found to be the optimal length of sleep for maintaining healthy blood pressure," Young said. "We found that too little sleep (less than seven hours) and too much sleep (anything more than seven hours) for adults also had a negative impact.

"Permanent night shift workers showed the greatest elevation in blood pressure, but those people working rotating shifts also showed elevated levels, although not as significant as permanent night shift workers.

"Our data also show that short sleep plus shift work has an additive negative effect on blood pressure."

The body's circadian clock governs almost all processes in the human body, including metabolic function, cognition, heart rate and sleep-wake behaviour. Disruptions to the body's normal biological rhythms can leave the body out of sync, creating circadian strain, and thus negative consequences.

"Challenges that disrupt anticipation to daily light-dark cycles, food intake, and activity cues that are induced by non-traditional behavioural and lifestyle factors, like shift work, can adversely impact maintenance of normal biological rhythms at the systemic and cellular level, thereby compromising organ function," Young said.

"Blood pressure follows a well-characterised circadian rhythm, so disruption of this rhythm has significant implications for cardiovascular health outcomes,” he noted.