Fatty liver may up risk of personality disorders by 3x: Study

LONDON: People with non-alcoholic fatty liver disease (NAFLD) are around three times more likely to have a personality disorder than those without the disease, a new study has revealed.

NAFLD is a global health problem and multi-faceted disease, with the main risk factors being obesity and insulin resistance.

Whilst in its early stages there may be few symptoms, the disease can progress to cirrhosis and liver failure in at risk individuals such as diabetics.

Scientists at the University of Birmingham in the UK call for NAFLD patients to be screened for personality disorders.

If identified, these mental health disorders should be treated before the patients begin trying to control their diet and exercise more, they said.

"Finding an increased prevalence of personality disorders in NAFLD patients is particularly striking -- signifying that it's not an issue associated with all liver disease, but just those with NAFLD," said Jonathan Catling, co-author of the study.

"Importantly, it appears not to be a general mental health issue, as neither anxiety nor depression were found to be significantly different between the groups - despite both psychiatric disorders often being associated with chronic liver disease," Catling added.

The study, published in the journal BMC Gastroenterology, also notes that, although simple measures such as changes in diet and increased exercise are proven to prevent disease progression in NAFLD, it is often difficult to persuade patients to follow dietary and exercise programmes.

"Our findings suggest an urgent need to examine attitudes towards diet and exercise so that we can better understand how to motivate NAFLD patients and deliver more effective treatment - preventing disease recurrence after liver transplantation," said Catling.

Researchers suggest necessary changes to diet and exercise regime that prevent disease progression into the more serious, irreversible stages of the disease.